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  • Active substances: Tylosin
  • Oral powder for the treatment of infections caused by tylosin susceptible microorganisms. It is very effective in the treatment of mycoplasmosis, spirochetosis, vibriosis and chlamydiosis in animals and birds
  • Target species: cattle, swine, poultry
  • Administration: oral
  • Packing: 25 g, 50 g, 100 g, 1000 g, 10 kg



1 g product contains:

Tylosin tartrate…………………………………………….. 580 mg

Excipient ………………………………………………….. 1 g

Excipient: Lactose monohydrate.



Tylosin is an active macrolid antibiotic against gram positive cocci (Staphylococcus spp., Streptococcus spp.), gram positive bacteria (Bacillus anthracis, Corynebacterium spp., Clostridium spp., Listeria, Erysipelothrix), gram negative bacteria (Haemophylus spp., Pasteurella spp., Brucella spp., Mycoplasma, Chlamidia and Rickettsia).

Tylosin binds to the 50 S ribosomes in the micro-organisms cell wall and produce the inhibition of protein synthesis. In therapeutic concentrations, it acts bacteriostatically, and in high doses or in case of very sensitive micro-organisms also has bactericidal action.

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Calves, swine, and poultry (broiler chicks, changing young, laying hens, turkey hens).



It is very effective in the treatment of mycoplasmoses, spirochetosis, vibriosis and chlamydiosis in animals and birds.

Calves: treatment of lung disorders with Mycoplasma and/or Pasteurella multocida.

Swine: treatment and control of respiratory infections  (Mycoplasma spp., Pasteurella spp., Campylobacter spp., etc) and dysentery caused by Brachyspira hyodysenteriae.


- treatment of chronic respiratory diseases caused by Mycoplasma gallisepticum in broilers and changing young

- treatment of respiratory diseases and necrotic enteritis in laying hens

- treatment of infectious sinusitis caused by  Mycoplasma gallisepticum in turkey hens



The product is administered orally, individually, or in the feed, through the drinking water, milk or milk substitute, in the feed, for at least 5 days.

Vitei:  in milk or milk substitute: 80 mg powder /kg g.c./day (40 mg tylosin/kg g.c /day) divided into 2 doses.  Dissolve 1 g of powder in a litre of milk or milk substitute and given twice a day for 7-14 days.


- in the drinking water: 0,25 – 0,5 g powder in 1 liter water (25 -50 mg tylosin /kg g.c)

- in the feed: 0,5 – 1 g powder in 1 liter water (500 g – 1 kg powder/tonne feed)

The treatment is continued 24 hours after the clinical manifestations subside.

Chicks, hens, changing young:

- in the drinking water: 1 g powder in 1 liter water (35 mg tylosin /kg g.c)

- in the feed: 1 g powder in 1 kg food

Turkey hens:

- under 10 weeks: 1 – 1,2 g powder in 1 liter of drinking water

- over 10 weeks: 0,5 – 0,6 g powder in 1 liter of drinking water

To assure a proper dosage the body weight should be determined as precisely as possible.

If the animals do not present an improved state of health, consult the veterinarian for the revaluation of the diagnosis.



Do not administer to animals with hypersensitivity to tylosin or other macrolide antibiotics (erythromycin).  Tylosin may produce severe diarrhea in the oral administration in calves.

Tylosin may act antagonist with lincosamides. When administered together with digitalis, glycosides may increase in concentration in the blood, thus increasing the toxicity thereof.In swine it has been reported as adverse effects rectal mucosa edema and mild anal swelling with pruritus, erythema, and diarrhea. There is no information available regarding the harmful action of tylosin taken orally in pregnant animals, therefore it is considered that TYLOSIN powder FP 60% can be administered safely to pregnant animals. It can be administered to laying poultry in compliance with the waiting time, respectively with the limit of residues in meat and eggs laid down in Regulation (EC) no. 37/2010.

Not be used simultaneously with penicillins, cephalosporins or lincomycin because these substances decrease the antibacterial activity of tylosin. Tylosin is relatively safe in case of accidental overdose.  In the case of newly born piglets, were still isolated cases of shock to overdose. Tylosin is incompatible with palmitate chloramphenicol, succinate sodium chloramphenicol, macrolides (erythromycin, claritromicin, azitromicin).



Meat: calves, swine- 10 days; poultry- 4 days

Eggs: 4 days



Store at a temperature not exceeding 25 ° C.  Keep away from frost.  Protect from direct sunlight.  Store in a dry place, in the original packaging, tightly closed.



Bags containing 25 g, 50 g, 100 g, 1,000 g and bags containing 10 kg.



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