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MAGNESIUM SULFATE

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sulfat-de-magneziu
  • Active ingredients: Magnesium sulphate Powder for treatment of acute constipation, of the overload indigestion, poisoning, coprostasis, as an adjuvant to the animals with edema  Target species: horses, cattle, sheep, goats, pigs, dogs
  • Administration: Oral
  • Packing: 100 g, 1 kg, 10 kg

 

COMPOZITION

1 g of product contains:

Magnesium sulphate heptahydrate………………………… 1 g

Product does not contain excipients

 

PHARMACOTHERAPEUTIC ACTION

Magnesium is found in intracellular fluid, being in second place in the spread. It is an essential cofactor for many enzymes, especially fosfortransferazele, and plays a vital role in the reversible association of intracellular particles and binding of macromolecules to subcellular organs (eg ribosome and mRNA). Magnesium plays an important role in neurochemical transmission and muscular excitability and also in the central nervous system and cardiovascular system.

Administered orally as osmotic laxative in hypertonic solution has a low absorption, retain water in the intestinal lumen to isotonisation. Magnesium sulfate attracts water and thin tissues causing increased intestinal content, which has the effect of speeding stimulate peristalsis and bowel evacuation content. Magnesium sulphate as a saline cathartic, does not irritate gastrointestinal mucosa. Action magnesium sulfate oral occurs after 4-8 hours after administration.

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TARGET SPECIES

Horses, cattle, sheep, goats, swine, dogs.

 

INDICATIONS

It is used in horses, cattle, sheep, goats, swine and dogs as a purgative to treat acute constipation if by overload indigestion, food poisoning and some chemical substances, coprostasis as an adjunct to animals to produce edema remove water retained in the body.

 

DOSAGE, ROUTE AND METHOD OF ADMINISTRATION

Product should be administered orally, usually a single dose, after preparing a salt solution of magnesium sulfate in a ratio of 1 part magnesium sulphate and 5 parts water, as follows:

- Horses: 200-500 g / animal

- Cattle: 400-800 g / animal

- Sheep, Goats: 40-100 g / animal

- Swine: 25-50 g / animal

- Dogs: 10-25 g / animal

 

CONTRAINDICATIONS, PRECAUTIONS AND ADVERSE REACTIONS

Not recommended for old and dehydrated animals and those with renal impairment. Animals under treatment will be supplied with sufficient water to prevent dehydration. Depressive effects of magnesium can be easily antagonized by intravenous administration of calcium salts (chloride or calcium gluconate). Normally, 20% of magnesium is absorbed systemically and excreted by the kidneys. If excessive absorption or elimination through the kidneys is insufficient, then there a hypermagnesemia and metabolic alkalosis may occur.

It can be used during pregnancy or lactation.

Oral saline purgativs may influence the absorption of other drugs taken simultaneously, due to reduction of their overall bowel. Action diminishes iron, tetracycline, streptomycin.

If overdose or in case of too little water supply massive elimination of fluids leading to dehydration may appear. This can be prevented by sufficient water supply. If doses exceed for cattle or animal suffering from intestinal and renal (absorption too intense, too slow elimination) may appear: lying, apathy, lack of reflexes (except eyelid and corneal reflex), hypothermia, slow breathing with deep breathing (sometimes snores), cardiac parameters being within normal limits instead. Do not administer both with drugs based on tetracycline, iron.

 

WITHDRAWAL PERIOD

Not applicable.

 

STORAGE

Store at temperatures below 25 ° C. Keep away from direct light.

 

PRESENTATION

Bags containing 100 g, 1 kg bags produced and packs of 10 kg product.

 

MANUFACTURER: SC PASTEUR – FILIALA FILIPESTI

PRODUCTS FROM THE CATEGORY: Vitamins for horses