1 tablet contains:
Acepromazine maleate…………………………………….. 10 mg
Excipients: sodium metabisulphite……………………… 1 mg
Other ingredients: Talcum powder, Magnesium stearate, Stearic acid, Microcrystalline cellulose, Lactose monohydrate, Colloidal silicon dioxide.
Acepromazine maleate, the active the principle of SEDAM product is a derivative of phenothiazine with antipsychotic properties and low toxicity. It also has antiemetic, anticonvulsant, hypothermic, hypotensive and antispasmodic properties. Phenothiazines blocks postsynaptic dopamine receptors in the central nervous system. Pharmacodynamic actions are determined by central recreational properties, represented by inhibiting the psychomotor activity, intestinal smooth muscle relaxation, producing peripheral vasodilatation.More info
It is recommended for dogs and cats for:
- Behavioral disorders
- Preventing boarding stress (automobiles, aircrafts)
- Small surgical interventions used as a preanestezic
- Control nervousness
- Preparation of animals for clinical examination
Administration is by the oral route. Dosage can be individualized, depending on the degree of sedation that is required.
- Dogs: 1 to 2 troches/10 kg g.c. (1-2 mg. a.s. / Kg g.c).
- Cats: 1 to 2 tablets / 5 kg g.c. (2 to 4 mg a.s. / Kg g.c);
To prevent harm of transport the dose is administered 15-30 minutes before boarding.
If animals do not show an improvement in health your veterinarian should be consulted for diagnosis reassessment.
Do not use in animals with s hepatic, cardiac and renal dysfunctionl and to animals with known hypersensitivity to one of the product components. Terrier breed dogs may exhibit resistance. Do not use in dogs with known hypersensitivity like Boxer breed that is showing sensibility to hypotensive and bradycardic effects of acepromazine maleate. In case of using in surgery, animals which are pre-treated with Acepromazine shall receive lower doses of general anesthetics. To avoid poisoning be strictly comply with the recommended dose. The most common side effects of acepromazine are cardiac (hypotension, bradycardia), manifested especially in dogs. Occasionally, after administration of the product, animals may show signs of aggression or contradictory to central nervous system stimulation.
It is not known the existence on use of contraindications for the females during mating, gestation and lactation. Do not associate with organophosphorus ectoparasite products, including antiparasitic collars. Should not be administered concomitantly with antidepressants agents of central nervous system _ (barbiturates, narcotics, etc.). because it can increase depression. Do not administer simultaneously with quinidine (can cause cumulative side effects on cardiac system) with propranolol (may cause increases in blood concentrations for both drugs) and epinephrine (causes vasodilation and increased heart rate).
Do not use in combination with procaine hydrochloride because it enhances the activity of acepromazine.
Products antacids can cause diarrhea and reduced gastrointestinal absorption of orally administered acepromazine. Acepromazine phenytoin metabolism slows, when used simultaneously. The studies showed that diazepam and glycopyrrolate are incompatible with acepromazine. The studies performed have shown that administration in dogs doses of 20-40 mg / kg bw for a period longer than 6 weeks produced no adverse effects. Dogs that were given oral doses gradually up to 220 mg / kg be showed symptoms of pulmonary edema and hyperemia of the internal organs, but dosage not proved to be fatal for any of the cases. The studies showed that diazepam and glycopyrrolate are incompatible with acepromazine.
Store at temperatures below 25 ° C. Protect from light. Store in a dry place.
Vials of 50 tablets.
Cardboard boxes containing 2 blisters of 10 tablets each.
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