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  • Target species: bovine, ovine
  • Administration: hypodermal
  • Packaging: 50 doses



For 1 ml: Active substance

Inactivated culture and anatoxine of Cl. perfringens, types

- type A ≥ 80 DLM/ml

- type B ≥ 400 DLM/ml

- type C ≥ 400 DLM/ml

- type D ≥ 80 DLM/ml

Active substance included in a minimum vaccine dose (2 ml), inoculated repeatedly at the rabbit, induces a seric title after the inactivation of min.10 U.I. antitoxin beta/ml, respectively of min. 5 U.I. epsilon antitoxin /ml, alfa antitoxin ³ 2 UI.


Aluminum hydroxide ……….0,2 ml (2,8 – 3,4 mg Al2O3)

Aldoform …………………4,8 mg (of which free < 0,05 g%)

Thiomersal (Sodium merthiolate)………………..< 0,01 g%



Bovine and ovine, starting from 2 months old.

More info


Rompervac ABCD is indicated for the active immunization of the bovine and ovine against the entero-toxiemies with Cl. perfringens: anaerobic enteritis of calves, anaerobic entero-toxiemy of sheep, anaerobic dysentery of lambs. It is used for the bovine and ovine, starting from 2 months old.

The preventive inoculation, in the enzootic areas, is applied in the spring, before the summering. The preventing inoculation is applied, too, for the animals that are transferred from the inducing areas where the disease enzootically develops. The necessity inoculation, in new focuses, is applied any time necessary, on the clinically healthy animals. The maintenance of immunity, at the vaccinated animals, is made by re-inoculations at every 6 months.



In bovine (calves of over 2 months), the vaccine is administered by deep injection (s.c.), in a dose of 5 ml, with rappel after 21 – 28 days.

In the adult ovine, the vaccine is administered by deep injection (s.c.), in a dose of 2 ml, with rappel after 21 – 28 days.

In lambs (of over 2 months), (calves the vaccine is administered by deep injection (s.c.), in a dose of 4 ml, in tho distinct points, with rappel after 21 – 28 days..



The sick animals or those with a transport stress are not vaccinated. The females in the last pregnancy month and during the first 2 weeks after lambing are not vaccinated. Systemic reactions: light increment of body temperature, up to 0,5°C, at the adult sheep and up to 0,6°C, at the calves and lambs, in the inoculation day and in the following day; a minor (4%) and temporary (2-3 days) decrease of the milk production at the sheep, as a cumulated effect of the vaccine and of the inoculation maneuvers. Local reactions: intumescence at the inoculation place, which is remitted within 48 hours – at the adult sheep and within 72 hours – at the lambs and calves; vaccine nodules of about 2 cm at 66,7% of the calves and at 62% of the lambs, respectively of about 1,5 cm at 52% of the adult sheep, which involuated, usually without complications, being noticeable at touching, with sizes of about 0,5 cm, at 6 weeks after the inoculation; up to 4% of the nodules at the sheep and 4,9% at the lambs may abscess, healing within 14 days. Such reactions are very usual for the adjuvant vaccines with aluminum hydroxide.

Although there have not been noticed after the inoculation with Rompervac ABCD, there are possible anaphylactic reactions, which may occur after the intake of biological products, like this vaccine. Consequently, it is recommended the surveillance of animals at 1 – 2 hours after the inoculation and, if necessary, it is administered an anti-hystaminic (e.g. epinephrine). If you notice serious reactions or other effects that are not mentioned in this prospect, please inform the veterinary. On the intake of 2 vaccine doses, no abnormal reactions were registered, others than those previously mentioned.

The vaccine is not inoculated otherwise than deeply. Before the inoculation, the vaccine must be brought to the room temperature and homogenized by agitation. The intake of vaccine will be made by sterile syringes and needles, and the inoculation place is disinfected with alcohol. After the unsealing of the phial, the vaccine must be used within 6 hours. The safety and efficacy of this vaccine, administered together with any other one (in the same day or in different days) were not proven. In any population of animals, there may be individuals that do not answer well to immunization. The success of inoculation depends on the correct maintenance and intake of vaccine and on the answer capacity of the animal. The efficiency of the vaccine may be influenced by the genetic constitution, age, infections and inter-current treatments, the presence of maternal antibodies, nourishment, hygiene and stress.

The vaccine includes aldoform, which is toxic: it may produce the irritation and sensitivity of the skin, eyes and mucous of the respiratory system. The handling of vaccine must be carefully made, avoiding its direct contact to the skin, eyes and mucouses. In case of accidental self-injection, it is let to bleed and is washed with water. If a local reaction occurs, it is required the physician’s intervention, showing the prospect or label of the product. The persons with a known hyper-sensitivity to the product compounds must avoid the contact with it.



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To be kept and transported under refrigeration conditions (2 – 8°C). To be protected against frost. To be protected against light.



Phials with 50 doses.



PRODUCTS FROM THE CATEGORY: Vaccines for ruminants