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PYRATEL EQ

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Pyratel-EQ
  • Active substances: Pyrantel
  • Paste for the control of endoparasitiasis caused by nematode (Strongylus vulgaris, edentatus and equinus, Oxyurus equi, Parascaris equorum) and cestode (Anaplocephala spp.)
  • Target species: horses
  • Administration: orally
  • Package: 30 ml

 

COMPOSITION

1 ml paste contains:

Pyrantel (as pamoate)……………………………….. 132 mg

Methylparahidroxibenzoat…………………………………… 2 mg

Propylparahidroxibenzoat……………………………….. 0.2 mg

Excipients: Propilenglicol, PVP K 30, Polisorbat 80, Glycerine, Lactose, Magnesium stearate, Sorbitol, Alcohol cetostearilic, Xantam gum, Sodium metabisulphite, Purified water.

 

PHARMACOTHERAPEUTIC ACTION

PYRATEL EQ, by its active component pyrantel pamoate from the tetrahidropirimidine cathegory is active against gastrointestinal nematodes and some cestodes, acting as a neuromuscular blocking agentthat paralyzes the parasite’s muscles.

This permits that the normal intestinal peristaltic moves reject the parasite.

Pyrantel pamoate is little absorbed in the intestine. The maximum concentration in the blood is reached after 2 or 3 hours. It is rapidly metabolized and it is removed at a rate of 35- 50% in the most part of fecals, being most active against the parasites in the large intestine.

Because of its colinergic action (nicotinic type) it is not recommended to be associated with parasimpaticomimetic substances and organophosphorical compounds.

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TARGET SPECIES

Horses

 

INDICATIONS

It is used in horses to control endoparasitiasis caused by nematodes (Strongylus vulgaris, edentatus and equinus, Oxyurus equi, Parascaris equorum) and cestodes (Anaplocephala spp.).

 

POSOLOGY, ROUTE AND METHOD OF ADMINISTRATION

The dose of  PYRATEL EQ, paste, administered per os (orally), varies according to the weight of the treated animal, such as:

- against nematodes the dosage is 660 mg pyrantel base/100 kg body weight, a notch respectively (5 ml paste) / 100 kg body weight. The content of a syringe assures the treatment of   600 kg body weight.

- against cestodes (Taeniasis) double dosage is used comparatively with those used against gastrointestinal nematodes , 10 ml paste/ 100 kg body weight.

Foals aged 2-8 months will be monthly dewormed.

Pregnant mares should be dewormed 1 month before calving, repeating the treatment at 10 – 14 days after calving.

Horses and ponies over 8 months of age are dewormed every 6 weeks.

For administration, the ring on the graded syringe piston is fixed according to bodyweight, the syringe is introduced in the oral cavity of the horse, in the interdental space, as deep as possible, using the drug at the base of the tongue. Immediately after administration, the animal head is raised for a few seconds. Before the paste administration make sure there is no feed in the oral cavity. In case of reinfestation, ask for the veterinarian advice regarding the frequence of product administration and the repeating of the treatment.

 

CONTRAINDICATIONS, PRECAUTIONS AND ADVERSE REACTIONS

Do not use in feeble animals. Used according to the instructions there are no adverse reactions.

When administered make sure there is no feed in the oral cavity. It can be used during pregnancy and lactation. It is not recommended the simultaneous treatment with products that contain: morantel, levamisol, piperazine and organophosphorical compounds.

Regarding the overdose, pyrantel pamoate is toxically methoderat. Administered in horses in a 20 times larger dose that the recommended one it has no adverse reactions.

 

WITHDRAWL TIME

Meat and organs: zero days

 

STORAGE

Temperature below 25°C. Keep away from direct light and freezing.

 

PACKAGE

Plastic syringe containing 30 ml of product, in individual cardboard boxes.

 

MANUFACTURER: S.C. PASTEUR – FILIPEŞTI BRANCH

PRODUCTS FROM THE CATEGORY: Antiparasitic for horses