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FOAMING PESARIES AND EFFERVESCENCES

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Pesarii
  • Active substances: Chlorhydrate oxytetracycline, sulphate neomycin
  • Pesaries recommended in placenta retentions, uterine and vaginal prolapsis, distocies, different surgical interventions on the uter, cervicites, vaginites, metrites, endometrites
  • Target species: horses, bovines, ovine, goats, swine, dogs
  • Administration: intra-vaginal, intra-uterine
  • Packaging: 25 pesaries

 

COMPOSITION

1 pesary contains:

Chlorhidrate oxytetracycline…………………………… 250 mg

Sulphate Neomycin……………………………………….. 250 mg

Excipients : Citric acid, Sodium bicarbonate, Sodium lauryl sulfate, Magnesium stearate,Talc, Polyvinylpyrrolidone K30.

 

PHARMACO-THERAPEUTICAL ACTION

By the association of two antibiotics (neomycine and oxiteracicline) the product establishes a bacteriostatic and bactericide synergic action over the Gram-positive and Gram-negative germs, frequently involved in the inflammatory processes of the genital tract. Due to the effervescence, the active substances are uniformly spread on the surface of vaginal or uterine mucous, diffusing in the tissues and umores.

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TARGET SPECIES

Horses, bovine, ovine, goats, swine, dogs.

 

INDICATIONS

The product is recommended for the horses, bovine, ovine, goats, swine and dogs in placentar retentions, uterine and vaginal prolaps, distocies accompanied by lesions of the tissues, different surgical interventions on the uterus, cervicites, vaginites, methrites, acute and chronic endomethrites.

 

POSOLOGY, ADMINISTRATION WAY AND MODE

The product is manually administered or by the aid of pense in the vaginal or uterine cavity. The doses and period of treatment are established depending on the species.

Horses, bovine: 4 – 6 pesaries daily, for 3- 4 days;

Ovine, goats, swine: 2 – 3 pesaries daily, for 2- 3 days;

Dogs: 1/2 pesaries daily, for 2- 3 days.

 

CONTRAINDICATIONS, CAUTIONS AND ADVERSE REACTIONS

It must not be administered for the horses of which meat is designed to the human consumption. It is not administered 3 days before and after the inoculations with live bacterial vaccins. It must not be used during the first pregnancy month. The association of the product with the calcium, magnesium, mangan, iron, aluminium salts may lead to the formation of certain inactive compounds of oxytetracycline.

The administration of the product concomitantly with the metrotrexat, due to the presence of neomycin, decreases its absorption, increasing the intestinal excretions and decreases at the same time the urinary excretion. Administered concomitantly with dimenhidrinate, this masks the incipient oto-toxicity symptoms induced by neomycin. The association with streptomicina, kanamicina, gentamicin, paramomicina and colistine that add their toxicity to the one of the neomycin sulphate may lead to the renal harm. The association of the product with anesthesic substances, due to the presence of neomycin, may produce a neuromuscular block.

 

WAITHDRAWL TIME

Meat: bovine, ovine, goats, swine – 4 days

Milk:  3 days

Do not use in horses whose meat is intended for human consumption.

 

MAINTENANCE CONDITIONS

To be kept at a lower temperature than 25°C. To be protected against frost. To be protected against the direct sunlight. The package must be kept well closed. To be maintained in a dry place.

 

EXPOSURE MODE

Bottles that include 25 pesaries.

 

MANUFACTURER: S.C. PASTEUR – FILIALA FILIPESTI

PRODUCTS FROM THE CATEGORY: Antibiotics for dogs