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MASTIKER E

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mastiker
  • Active substances: Eritromycin
  • Suspension recommended for the cows during the lactation period for the treatment of clinical, acute or chronic mastites with a staphilococci, streptococcic and piobacilar ethiology
  • Target species: bovines
  • Administration: intra-mammal
  • Packaging: syringe 6 ml

 

COMPOSITION

A syringe for the intra-mammal administration contains 6 ml suspension:

Erythromycin (base)……………………………………. 300 mg

Excipients:

Benzyl alcohol ……………………..…………….……… 60 mg

Neutralized and sterilized sunflower oil, Lanoline, Macrogol 200, Butilhidroxitoluen.

 

PHARMACO-THERAPEUTICAL ACTION

Erythromycin is an antibiotic of the group of macrolides, with a medium action spectrum, which includes Gram positive cocci (Streptococcus spp., Stafilococcus spp., including the penicillin-resistant ones, pneumococci, enterococci), Gram negative cocci (gonococi, meningococi), clostridii (C. tetani, perfringens, botulinum), B. subtilis, Sarcina lutea, Corinebacterium spp., as well as some Gram negative baccili (Brucella, Pasteurella, Haemophylus), spirochete (Leptospira), micoplasmas, ricketsii, wide viruses certain protozoa (Entamoeba, Toxoplasma, Trichomonas). Erythromycin has a bacteriostatic/ bactericide action, depending on the dose, consisting in the inhibation of bacterial proteic synthesis. It is active against Staphylococcus aureus, Streptococcus agalactiae and Streptococcus uberis, Streptococcus dysgalactiae, bacterias that produce about 90% of the mastitis cases. The product is generally distributed uniformly in the harmed quarter. However, the presence of edemas, blockage of the milk channels and hardening of blood circuit in the serious or chronic forms may cause an inequal distribution of the antibiotic.

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TARGET SPECIES

Cows (during the lactation period).

 

INDICATIONS

MASTIKER E – suspension for the intra-mammal administration is recommended for the cows during the lactation period for the treatment of acute or chronic mastitis, produced by germs sensitive to erythromycin – mainly streptococci, stafilococci (including penicilino-rezistant), piobaccili.

 

POSOLOGY, ADMINISTRATION WAY AND MODE

Dose: 1 syringe- 10 ml product

Administration:

- the product is intra-mammal administered, after the full milking and hygienization (washing and disinfection);

- it is administered one syringe at each quarter at 12 hours.

Period of treatment:

- 2 – 3 administrations in the case of acute mastitis.

- 3 – 4 administrations in the case of chronic mastitis.

The cow will not be milked for at least 6 hours after which it was administered the treatment. The milk obtained during the treatment is not administered for human consumption.

If the animals don’t show an improvement of the health state, the veterinary will be consulted, for the re-evaluation of the diagnosis.

 

CONTRAINDICATIONS, CAUTIONS AND ADVERSE REACTIONS

Occasionally, possible local or systemic allergic reactions. MASTIKER E is recommended for the treatment of clinical, acute and chronic mastitis for the cows during the lactation period. Avoid the concomitant administration with lincomycin, clindamicina, penicilina and chloramphenicolul. The metabolism of methylprednisolone may be inhibited by the simultaneous administration with erythromycin. On overdosing, contrary reactions, allergic reactions, respectively, may occur.

 

WAITING TIME

Meat and organs: 7 days;

Milk: 3 days.

 

MAINTENANCE CONDITIONS

To be kept at a lower temperature than 25°C. To be protected against frost. To be protected against the direct sunlight. To be maintained in a dry place.

 

EXPOSURE MODE

The product Mastiker E is pacjed in single use syringes, provided with adapter and cover, including 6 ml suspension with intra-mammal administration.

 

MANUFACTURER: S.C. PASTEUR – FILIALA FILIPESTI

PRODUCTS FROM THE CATEGORY: Antibiotics for ruminants