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GENTOCIN OTIC

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Gentocin otic
  • Active substance: Gentamicin sulphate, dexamethasone
  • Otic solution for the treatment of polymicrobial etiology of acute otitis externa caused by bacteria resistant to other antibiotics
  • Target species: Dogs, Cats
  • Administration: otics route
  • Packing: 7,5 ml

 

COMPOZITION

1 ml contains:

Gentamicin Sulfate……………………………… 3 mg

Dexamethasone………………………………….1 mg

Excipients: Ethyl alcohol, Glycerin, Polyethylene glycol 400, Distilled water, Glacial acetic acid.

 

PHARMACOTHERAPEUTIC ACTION

Gentamicin is an aminoglycosides group antibiotic produced by Micromonospora purpurea with bactericidal action by setting the 30S ribosomal subunit of the bacterial cell, causing disruption of RNA messenger, which results in the synthesis of polypeptides atypical or inadequate toxic bacterial metabolism. Gentamicin is active both in the multiplication phase and in the rest of germs.

Spectrum of activity is wide including Gram-negative bacteria (Pseudomonas aeruginosa, Proteus spp, Escherichia coli, Klebsiela spp, Enterobacter spp) and Gram-positive (Staphylococcus spp, Streptococcus spp.)

Gentamicin is effective through local applications of primary and secondary eye infections, particularly those caused by bacteria resistant to beta-lactamic antibiotics.

Dexamethasone is a synthetic corticosteroid with anti-inflammatory effect 30 times more powerful than hydrocortisone. Is very active in local applications. Association with otic solutions reduces healing time due to anti-inflammatory and anti-allergic properties.

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TARGET SPECIES

Dogs and cats.

 

INDICATIONS

GENTOCIN OTIC is used for the treatment of external otitis shown in polymicrobial etiology caused by germs resistant to other antibiotics.

 

DOSAGE, ROUTE AND METHOD OF ADMINISTRATION

Clean the animal’s ear with a wax removal solution – Otto cleans. GENTOCIN otic solution shall be instilled into the ear canal, then gently massage the ear for a good diffusion of the drug into the ear channel. Is administered by 2 to 4 drops 2 times / day for 5-6 days.

If animals do not show an improvement in health your veterinarian should be consulted for diagnosis reassessment.

 

CONTRAINDICATIONS, PRECAUTIONS AND ADVERSE REACTIONS

Do not use during pregnancy.

Safety of the product has not been established during lactation. Use only according to the benefit / risk assessment by the responsible veterinarian. Simultaneous use of other ototoxic substances and / or nephrotoxic enhances ototoxicity and / or nephrotoxicity of gentamicin. Simultaneous administration of neuromuscular blocking potentiate preexisting neuromuscular blockage.

Rarely allergic reactions can occur.

Incompatibilities in solutions with: amphotericin B, ampicillin, benzylpenicillin, carbencillin, cephalothin, chloramphenicol, hemisuccinat, heparin, methicillin, oxacillin, vitamin B complex.

 

WITHDRAWAL PERIOD

Not applicable.

 

STORAGE

Store at temperatures below 25 ° C. Protect from direct sunlight. Protect from freezing.

 

PRESENTATION

Bottles provided with dropper, of each 7,5 ml of otic solution.

 

MANUFACTURER: SC PASTEUR – FILIALA FILIPESTI

PRODUCTS FROM THE CATEGORY: Varia