1 ml injectable solution contains:
Gentamicin (as sulphate) ……………………………….. 100 mg
Benzyl alcohol ……………..…………………..……… 10 mg
Sodium meta-bi-sulphure, Sodium sulphite,Disodic edetate, Purified water for the injectable solutions.
Gentamicin is an antibiotic of the group of aminoglicozines obtained from cultures of Micromonospora purpurea with an obviously bactericide effect, independently of the multiplication stage of germs (the latency stage or the logarithmic multiplication stage). The bactericide activity refers to the Gram-negative and Gram-positive germs, (Pseudomonas spp., Klebsiela spp., Enterobacter spp., Serratia spp., E.coli, Proteus spp., Salmonella spp., Actinobacillus spp, Bordetella bronchiseptica, Fusobacterium, Haemophylus, Campylobacter spp Staphylococcus, Streptooccus, Actinomyces, Erysipelothrix, Clostridium, Listeria etc.)
Gentamicine has also an action over Treponema hyodysenteriae., Mycoplasma, Leptospira.
Gentamicin, after the intramuscular administration, reaches the maximum blood concentration after 30-60 minutes and is removed under the active form through the kidneys, into the urine, reaching bactericide concentrations. Administered on the mucouses (digestive, conjunctive) it is a little absorpted in the general circulation, but it acts well locally.More info
Bovine, swine, dogs and cats.
For the bovine, swine, dogs and cats, in the local or systemic infections caused by gentamicin sensitive microorganisms of the respiratory, gastro-intestinal, uro-genital tract, septicemias, omphalites, meningitis, artritis, pyoartritis, mastitis, skin infections, eye and ear infections.
It is administered intramuscular or intravenous, slowly, for the irascible or restive carnivorous, the subcutaneous may be chosen.
Doza este de 4 mg substanţă activă/ kg g.c
Bovine, suine: 4 ml/100 kg g.c., i.m. sau i.v.
Tineret porcin, câini şi pisici: 1 ml/ 25 kg g.c. i.m., i.v. sau s.c. (în cazuri speciale).
This is repeated every 12 hours for the first 1-2 days and within 24 hours the following day for 3-5 days. Treatment should be followed at least two days after the disappearance of clinical symptoms.
If animals do not show an improvement in health veterinarian should be consulted for diagnosis revaluation.
Hyper-sensitivity to gentamicin or other aminoglicozide. It is not administered on the animals with a serious renal insufficiency, serious vestibular disorders or on the pregnant females. It is not administered concomitantly with other aminoglicozidic antibiotics, with anesthetics, micro-relaxing substances or nephro-toxic substances. It will be avoided the administration combined with chloramphenicol, as well as the administration of gentamicin with other antibiotics (ampicillin, carbenicillin, cephalosporins, erythromycin) in the same syringe, sulfamides, vitamins of the B complex, or with heparine. The daily overdosing or the extension of the treatment over 6-7 days may lead to nephro-toxicoses. It must be carefully used for the cats. The amino-glycosides may produce neuro-muscular blockage, facial edema, peripheral neuropathy and hyper-sensitivity reactions. The hematologic and hepatic effects may rarely produce. It is not recommended during the pregnancy period.
The amino-glycosides must be carefully used together with other neurotoxic, nephro-toxic and oto-toxic medicines: amfotericin B, other amino-glycosides, aciclovir, bacitracine (parenteral use), cisplatun, metoxifluran, polimixin B or vancomicin. On the use together with beta-lactamic antibiotics and amino-glycosides, it may produce the synergy against Pseudomonas aeruginosa and enterococci. The overdosing may produce oto-toxicity and nephro-toxicity. It is not administered concomitantly with other aminoglicozidic antibiotics, with anesthetics, micro-relaxing substances or nephro-toxic substances.
Meat and organs: Cattle, swine – 28 days;
Milk: Cattle – 7 days.
To be kept at a lower temperature than 25°C. To be protected against frost. To be protected against the direct sunlight. Store in the original package.
Glass bottles of 50 ml,100 ml.
PRODUCTS FROM THE CATEGORY: Antibiotics for dogs