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ERYTHROMYCIN 6%

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Eritromicina-6proc
  • Active substances: Erythromycin
  • Powder for the treatment of the infections produced by erythromycin sensitive germs
  • Target species: bovines, rabbits, poultry
  • Administration: oral
  • Packaging: 100 g, 1 kg

 

COMPOSITION

1 powder gram contains:

Tiocianate erythromycin………………………………….. 60 mg

Excipient q.s.ad………………………………………………. 1 g

Excipient: Mono-hydrate lactose, Mono-hydrate citric acid

 

PHARMACO-THERAPEUTICAL ACTION

Erythromycin is an antibiotic of the macrolide group, with a wide action spectrum, which includes: Gram positive cocci (Streptococcus spp., Stafilococcus spp., including the penicillin resistant ones, pneumococci, entheroccoci), Gram negative cocci (gonococci, meningococci – light meat in vivo tetani, perfringens, botulinum), B. subtilis, Sarcina lutea Corinebacterium spp ., as well as certain Gram negative baccili, (Brucella, Pasteurella, Haemophylus), spirochetes (Leptospira ), micoplasmas, ricketsi, large viruses, certain protozoa ) (Entamoeba, Toxoplasma, Trichomonas). Erythromycin doesn’t have any action over the enterobacteriaceas Salmonella, Aerobacter, E. coli, Pseudomonas, Proteus, Klebsiella), fungi and mushrooms. Erythromycin has a bacteriostatic/ bactericide action, depending on the dose, by a mechanism similar to chloramphenicol, consisting in the inhibation of the bacterial proteic synthesis.

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TARGET SPECIES

Bovine (new born calves), rabbits and poultry (hens, turkey).

 

INDICATIONS

Erythromycin 6% is recommended for the treatment of the disorders produced by erythromycin sensitive germs to:

Bovine (new born calves): infections of the respiratory and digestive apparatuses, arthritis, infectious pododermatitis, omfaloflebite

Rabbits: pasteurelloses, streptococci and staphylococci infections.

Hens: mycoplasmosis, pasteurellose, respiratory chronic disease, infectious sinusitis, staphylococci arthritis, streptococci infections.

Turkey: aerosaculitte, infectious sinusitis, staphylococcus arthritis, streptococci infections.

 

POSOLOGY, ADMINISTRATION WAY AND MODE

Oral administration, after the dissolution in the drinking water or inclusion in the food:

Bovine (new born calves): (18-24 mg s.a./kg g.c./ day):

On the calves, the administration is individually made and is prepared ex tempore;

- 15-20 g Erythromycin 6%/50 kg body weight/ day, the dose being fractioned and administered 2 times daily (at 12 hours), for 3-5 days;

Rabbits (daily): (20 mg s.a./kg g.c./ day):

- 1 g Erythromycin 6%/3 kg body weight included in the fodder, for 3-5 days;

Hens, turkey (daily): (20 mg s.a./kg g.c./ day):

- 1,375 kg Erythromycin 6% /1000 L water, for 3-5 days.

or 14 g Erythromycin 6% /10 liters of water in the household system;

- 1,5 kg Erythromycin 6%/1000 kg fodder, for 3-5 days

To ensure proper management of a dose , the body weight of the animals should be determined as accurately as possible . Medicated water should be freshly prepared every 24 hours. For maximum efficiency , the medication should be combined with good management practices ( hygiene , proper ventilation , avoid overcrowding ) .

If the animals don’t show an improvement of the health state, the veterinary will be consulted, for the re-evaluation of the diagnosis.

 

CONTRAINDICATIONS, CAUTIONS AND ADVERSE REACTIONS

It will not be administered for the adult bovine. It will be avoided the treatment of allergic animals to erythromycin or of the animals with hepatic disorders. The allergic reactions may rarely occur. Occasionally, erythromycin orally administered may cause gastro-intestinal disorders (diarrhea, belch states, anorexia). The powder must not be administered as that.

On the treatment in mass, by fodders or drinking water, it is recommended the preparation of pre-mixes, for an appropriate homogenization. The medicated water must be entirely consumed, on the preparation day.

For a maximum efficiency, the medication must be combined with good administration practices (an appropriate hygiene, correct aeration, lack of over-agglutination).

Except for the above mentioned contrary reactions, which occasionally occur, erythromycin is considered a medicine with a low toxicity. It may be used during the lactation, pregnancy period or in the blowing period. Erythromycin is contrary to lincomycin, clindamycin, chloramphenicol, methylprednisolone.

 

WITHDRAWL TIME

Meat and organs: Bovine (new born baby calves) – 3 days; Rabbits – 3 days; Poultry (hens, turkey) – 3 days

Eggs: Chicken- 4 days

Do not use on turkeys that produce eggs destined for human consumption.

 

MAINTENANCE CONDITIONS

To be kept at a lower temperature than 25°C. To be protected against frost. To be protected against the direct sunlight. To be maintained in a dry place, in original package, tightly closed.

 

EXPOSURE MODE

Bags with 100 g, 1 kg product.

 

MANUFACTURER: S.C. PASTEUR – FILIALA FILIPESTI

PRODUCTS FROM THE CATEGORY: Antibiotics for rabbits