1 troche includes:
Enrofloxacin………………………………..…..… 50 mg
Excipients: Mono-hydrate lactose, Farina, Micro-crystalline cellulose, Stearic acid, Talc.
Enrofloxacin is a chemo-therapeutic substance with a wide range and powerful anti-microbial action, even over the germs resistant to antibiotics. It is a fluorite 4-quinolona derived, taking part to the last generation of synthetic quinolones. It has the lowest toxicity of the whole group of quinolones.
The germicide action is issued by the inhibition of the DNA gyrase enzyme (type II, topoisomerases), with an important role in the synthesis of nucleic acids, which determines the death of bacterial cell. It acts bactericide on the Gram-positive and Gram-negative germs, micro-plasmas and Chlamydia.More info
Swine, dogs and cats.
The treatment of primary and secondary infections of the respiratory tract, gastro-intestinal tract, infections of the soft teguments and tissues, infections of the external auditive channel.
Swine: infections of the digestive and respiratory tract, caused by bacteria and micro-plasmas (enteritis, septicemias, salmonellose, stafiloccocs, mycoplasmosis), secondary bacterial infections, in the enteritis and viral respiratory diseases.
Dogs and cats: respiratory, digestive, genital-urinary infections, dermatitis.
The troches are orally administered for the swine, dogs and cats, individually or adjusted and embedded in the food.
Daily dose: 1 troche/ 10 kg body weight (5 mg active substance/ kg body weight) at 24 hours.
The period of treatment is 5 days.
If the animals don’t show an improvement of the health state, the veterinary will be consulted, for the re-evaluation of the diagnosis.
It is not administered for the horses. It is not administered for the pregnant, lactant in dogs and for the dogs with epilepsy antecedents. It is not administered for the canine young during the growing stage, because the articular cartilage may be irreversibly affected by fluoroquinolones. The administration of fluoroquinolones at the canine young up to the age of 12 months may provoke articular lesions (changes of the cartilages). Due to the fact that on the administration of quinolones, there have been registered the cases of cristaluria, the dehydration of animals must not be allowed. For the animals with renal and hepatic disorders, the doses will be adjusted to avoid the accumulation of medicine in the body.
The intake of high doses during the pregnancy may provoke the loss of fetus and a toxic state. The administration of high doses, for a long time, during the growing period at the dogs, produce cartilaginous erosions that lead to permanent limps. On the administration of products based on enrofloxacin, it was noticed that the contrary effects may occur quite rare. The following symptoms may occur on the respiratory apparatus: anorexia, belch, diarrhea, abdominal pains. The neurotoxic symptoms that may occur: decrease of the visual acuity, dizziness, cephalalgia and convulsions.
The dejection of breath on the respiratory apparatus may occur at the old animals. The allergic reactions that may occur are: rashes, photo-sensitivity, fever, leucopenia, thrombocytopenia, hemolytic anemia. The administration of enrofloxacin is counter-indicated during the reproduction period, because it may cause the death of the fetus.
It is not administered for the pregnant and lactant females.
It is only used according to the benefit/ risk evaluation, made by the responsible veterinary. The administration of antacids prohibits the absorption of enrofloxacin. It has a contrary action to chloramphenicol, macrolide antibiotics, tetracycline and un-steroid anti-inflammatory substances. The overdosing may produce digestive symptoms, like belch and diarrhea. Another consequence of overdosing may be the hemolytic. It is not recommended the concomitant administration of fluoroquinolones with nitrofurantoin. The fluoroquinolones increase the neurotoxic effects of cyclosporine.
Swine: meat and organs: 7 days.
To be kept at a lower temperature than 25°C. To be protected against the direct light and humidity.
White, polyethylene bottles that contain 30, 50 and 100 troches/ bottle.
Cardboard boxes with 2 blisters, 5 blisters or 10 blisters made of PVC/ AL of each 10 troches.
PRODUCTS FROM THE CATEGORY: Antibiotics for dogs