See menu

ENROFLOXACIN FP 10%

X
Enrofloxacina-10proc-sol.orala
  • Active substances: Enrofloxacin
  • Oral solution for the treatment of the infections of digestive and respiratory apparatus, caused by the germs sensitive to active substance (enteritis, septicemia, salmonellosis, staphylococci, micro-plasmosis); it is recommended, too, in the treatment of secondary bacterial infections in the viral diseases
  • Target species: calves, lambs, pigs, dogs, cats, poultry (chickens – young replacement, broilers and turkeys – broilers)
  • Administration: oral
  • Packaging: 50 ml, 100 ml, 500 ml, 1 l, 5 l

 

COMPOSITION

1 ml oral solution contains:

Enrofloxacin………………………………..…..… 100 mg

Excipients: Propylene glycol, Sodium hydroxide, Purified water.

 

PHARMACO-THERAPEUTICAL ACTION

Enrofloxacin is a chemo-therapeutic substance with a wide range and powerful anti-microbial action, even over the germs resistant to antibiotics. It is a fluorite 4-quinolone derived, taking part to the last generation of synthetic quinolones. It has the lowest toxicity of the whole group of quinolones.

The germicid action is issued by the inhibition of the DNA gyrase enzyme, with an important role in the synthesis of nucleic acids, which determines the death of bacterial cell. It operates with bactericide on the Gram-positive and Gram-negative germs, micro-plasmas and Chlamydia.

More info

TARGET SPECIES

Calves, lambs, pigs, dogs, cats, poultry ( chickens – young replacement, broilers and turkeys – broilers )

 

INDICATIONS

The product is recommended for the calves, lambs, fawns, pigs for the treatment of the infections of digestive and respiratory apparatus, caused by the germs sensitive to active substance (enteritis, septicemia, salmonellosis, staphylococci, micro-plasmosis); it is recommended, too, in the treatment of secondary bacterial infections in the viral diseases.

For the dogs and cats, the product is recommended in the treatment of respiratory, digestive, uro-genital infections, dermatitis caused by germs sensitive to the active substance.

For the hens (broilers) and turkey hens (broilers), is recommended in mycoplasmosis, chronic bacterial infections of respiratory type, colibacillose, pasteurellosis, infectious coryza, salmonellose, staphylococcus, hepatitis, arthritis caused by the germs sensitive to active substance.

 

POSOLOGY, ADMINISTRATION WAY AND MODE

Dose selection range given is based disease severity and susceptibility of the microorganism. ENROFLOXACIN FP 10% oral solution is given as follows:

Calves, lambs, fawns, pigs: in drinking water, milk or milk replacer from 2.5 to 5 mg as / kg bw / day.

For the treatment of mycoplasma infections and moderate:

- 1 ml product / 40 kg G. C. (2.5 mg a.i. / kg g.c) for 3 days

For severe infections and infections with Salmonella spp:

- 1 ml of product / 20 kg bw (5 mg to / kg bw) for 3 days

Chickens (Youth replacement broiler, broilers) and turkey (broilers): in drinking water to 10 mg / kg bw / day.

For the treatment of mycoplasma infections and moderate:

 – 1 ml of product / 1 liter of drinking water for 5 days

Dogs: drinking water 5-20 mg to / kg bw / day for 3-5 days according to the disease severitatatea.

Cats: drinking water to 5 mg / kg bw / day for 3-5 days according to the disease severitatatea.

If animals do not show an improvement in health veterinarian should be consulted for diagnosis revaluation.

CONTRAINDICATIONS, CAUTIONS AND ADVERSE REACTIONS

It must not be administered for the canine young up to 12 months old and for the dogs with epilepsy antecedents. It is not administered in case of hyper-sensitivity to the active substance or to any of the Excipients. Except for the potential articular disorders at the level of growing cartilages for the immature animals, the contrary reactions are quite rare. However, belches (hives), gastric irritation (anorexia, belches), fever or even leucopenia, thrombocytopenia and hemolytic anemia.

It cannot be used for the dogs during the pregnancy or lactation period. It is not used for the reproduction poultry within 2 weeks before the commencement of the blowing period. The administration of antacids prohibits the absorption of enrofloxacin.

It has a contrary action to chloramphenicol, macrolide antibiotics, tetracycline and un-steroid anti-inflammatory substances.

Due to the low toxicity of enrofloxacin, the overdosing danger is minimum. There may occur contrary and temporary reactions, of decreasing the mobility and cricks. It does not exist a specific antidote for the overdosing treatment. The treatment is symptomatic. It is not recommended the concomitant administration of fluoroquinolones with nitrofurantoin. The fluoroquinolones increase the neurotoxic effects of cyclosporine.

 

WAITING TIME

Meat and organs: Calves – 12 days; Lambs – 4 days; Fawns – 4 days; Pigs – 7 days; Hens (broilers) – 5 days; Turkey hens (broilers) – 12 days

It is not allowed the use for the layers that produce eggs for the human consumption.

 

MAINTENANCE CONDITIONS

To be kept at a lower temperature than 25°C. To be protected against the direct light and frost. Store in a dry place .

 

EXPOSURE MODE

The product is packed bottles including 50 ml, 100 ml, 500 ml, 1 L and 5 L oral solution.

 

MANUFACTURER: S.C. PASTEUR – FILIALA FILIPESTI

PRODUCTS FROM THE CATEGORY: Antibiotics for dogs