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AMPICILLIN 20%

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Ampicilina20proc
  • Active substances: Three-hydrate amoxicillin
  • Injectable suspension for the treatment of primary and secondary digestive, respiratory, urogenital infections, complications after the surgical interventions, produced by ampicillin sensitive bacteria
  • Target species: horses, bovines, ovines, goats, swine, dogs and cats
  • Administration: intramuscular
  • Packaging: 10 ml, 20 ml, 50 ml, 100 ml

 

COMPOSITION

1 ml contains:

Three-hydrate ampicillin .…..………………………….…200 mg

Excipients:

Methyl 4-hydroxybenzoate……..……………………..…2,0 mg

Propyl 4-hydroxybenzoate……………………………… 0.2 mg

Sodium carboxymethyl-cellulose, Polysorbate 80, Povidone, sodium citrate, Water for the injectable preparations.

 

PHARMACO-THERAPEUTICAL ACTION

The Ampicillin is a semi-synthetic penicillin derived from 6-amino-penicilanic acid. It is a bactericidal antibiotic with a wide range, acting based on a series of Gram positive germs (Actinomyces spp., Bacillus spp., Clostridium spp., Staphylococcus spp., Streptococcus spp.) and Gram negative (Actinobacillus spp., Bordetella spp., Brucella spp., E. coli, Pasteurella spp., Proteus spp. etc.).

It diffuses well through the placenta, in the kidneys and liver. The removal is mainly made by the kidneys, less by the bladder and milk.

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TARGET SPECIES

Horses, bovine, ovine, goats, swine, dogs and cats.

 

INDICATIONS

It is used for the treatment of primary and secondary digestive, respiratory, urogenital infections, complications after the surgical interventions, produced by ampicillin sensitive bacteria.

 

POSOLOGY, ADMINISTRATION WAY AND MODE

The product is deeply intramuscular administered (after the phial is well agitated), observing the following doses:

- horses, bovine: 2,5 – 5 ml product /100 kg g.c (5 – 10 mg.s.a./kg g.c) two times/ day; for 4 – 5 days.

- swine, ovine, goats: 2- 3,75 ml product / 50 kg g.c (8-15 mg s.a / kg g.c.) / two times/ day, for 4 – 5 days;

- swine: 0,5 ml product / 10 kg g.c (10 mg s.a / kg g.c.) /day, for 4 – 5 days:

- dogs, cats: 0,1 – 0,12 ml product/ 2 kg g.c (10 – 12 mg s.a./kg g.c.) / day, for 4 – 5 days.

In serious cases, on the veterinary’s recommendation, the doses can be increased.

If the animals don’t show an improvement of the health state, the veterinary will be consulted, for the re-evaluation of the diagnosis.

 

CONTRAINDICATIONS, CAUTIONS AND ADVERSE REACTIONS

It is not administered in case of hyper-sensitivity to the active substance or to any of the Excipients. To be carefully administered for the animals with renal insufficiency. On certain animals, it may produce a temporary anemia. It may be used during the pregnancy and lactation period.

Avoid the concomitant administration of ampicillin with the chloramphenicol, tetracycline, gentamicin, lincomycin and the alkaline substances.

In the case of overdosing, there may occur skin, gastro-intestinal reactions (belches, abdominal pain, and diarrhea) and hardened breath. In case of accidental self-injection, immediately require the physician’s advice and show him the prospect of the product or the label.

 

WAITING TIME

Meat and organs: Horses, Goats – 6 days; Bovine, Ovine, Swine – 14 days;

Milk: Bovine, Ovine, Goats – 3 days.

 

MAINTENANCE CONDITIONS

To be kept at a lower temperature than 25°C. To be protected against light. To be protected against frost.

 

EXPOSURE MODE

Phials of  glass of 10 ml, 20 ml, 50 ml, 100 ml injectable suspension, provided with a rubber stopper and metal cover.

 

MANUFACTURER: S.C. PASTEUR – FILIALA FILIPESTI

PRODUCTS FROM THE CATEGORY: Antibiotics for horses